Matthew R. Bennett

Assistant Professor of Biochemistry & Cell Biology
Dr. Bennett’s website

Matthew R. Bennett joins the Rice faculty as assistant professor in the Department of Biochemistry & Cell Biology.

Bennett’s research spans the boundary between experimental and theoretical molecular systems biology. He says: “I am particularly interested in the dynamics of gene regulation ─ from small-scale interactions such as transcription and translation, to the large-scale dynamics of gene regulatory networks. I use a hybrid experimental and computational approach to uncover the underlying design principles governing native gene networks and to use these concepts to design novel synthetic circuits.”

This research area interests him, he says, because the dynamics of gene regulation are still poorly understood. Synthetic biologists hope to one day arrive at a complete mathematical description of genomic function ─ to do so requires a deep understanding of all processes affecting gene regulation. Bennett finds it exciting to be able to use both his theoretical physics background and his training in experimental biology to uncover the fundamental processes lying behind this new field.

Bennett’s research will greatly enhance the ability to design and predict the dynamic responses of synthetic gene networks. Such an understanding will be critical to the long-term goal of engineered gene networks with real-world applications, such as the production of biofuels, biologic drugs, and even gene-based therapeutic treatments.

Why did he choose Rice?  He says he was impressed by the collaborative atmosphere at Rice which is very different from many universities, which can be riddled with dog-eat-dog politics. The small-college feel, the motivated and bright students, and the first-rate research facilities combine to make Rice an ideal work environment.

He goes on to say: “I really get the sense that everyone at the university wants to see me succeed, and I have been surprised at how helpful everyone has been. It is very refreshing.”

As with most scientists, Bennett is excited by phenomena that are either unexplained or previously undiscovered. He explains, “Nothing drives me more than the pursuit of the unknown. Beyond that, I draw a lot of inspiration from my friends and family, my past advisors, and pretty much any person who has ever asked the question “why?”

Bennett comes to Houston with his wife of six years, Rebekah, a lawyer.